मोटापा और चयापचय जर्नल

खुला एक्सेस

हमारा समूह 1000 से अधिक वैज्ञानिक सोसायटी के सहयोग से हर साल संयुक्त राज्य अमेरिका, यूरोप और एशिया में 3000+ वैश्विक सम्मेलन श्रृंखला कार्यक्रम आयोजित करता है और 700+ ओपन एक्सेस जर्नल प्रकाशित करता है जिसमें 50000 से अधिक प्रतिष्ठित व्यक्तित्व, प्रतिष्ठित वैज्ञानिक संपादकीय बोर्ड के सदस्यों के रूप में शामिल होते हैं।

ओपन एक्सेस जर्नल्स को अधिक पाठक और उद्धरण मिल रहे हैं
700 जर्नल और 15,000,000 पाठक प्रत्येक जर्नल को 25,000+ पाठक मिल रहे हैं

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इस पृष्ठ को साझा करें


After Hematopoietic Cell Transplantation in Severe Mucopolysaccharidosis Type I (Hurler Syndrome), Metabolic Syndrome and Cardiovascular Risk Factors

Julia Berger

Although hematopoietic cell transplantation saves lives, it comes with an increased risk of cardiovascular disease over time and requires frequent long-term monitoring. In mucopolysaccharidosis type IH (Hurler syndrome), a disease with known involvement of the coronary arteries, this treatment has significantly extended survival. Metabolic disorder - a star grouping of focal stoutness, hypertension, low high-thickness lipoprotein cholesterol, raised fatty oils, and fasting blood glucose — is related with expanded cardiovascular gamble, and happens when any at least 3 of these 5 parts is available inside a solitary person. After Hurler syndrome transplant, the incidence of metabolic syndrome and its components are unclear. Review of all long-term hematopoietic cell transplant survivors with Hurler syndrome under the age of nine for metabolic syndrome-related factors: high blood pressure, obesity, low HDL cholesterol, elevated triglycerides, and fasting blood glucose are all risk factors. Twenty of the sixty-three patients who were examined had aspects of the metabolic syndrome that could be examined. Age at transplant, sex, number of transplants, pretransplant radiation, or percent engraftment were not significantly different between those with and without these data. For the 20 patients with data, the median follow-up period following transplantation was 14.3 years. In this group, only one patient (or 5%) met the metabolic syndrome criteria. One or more of the metabolic syndrome’s components were present in 53% of the patients: 40% of people had high blood pressure, which was the most common. In this group of long-term Hurler syndrome survivors, metabolic syndrome is not common. However, almost half of the patients had one or more metabolic syndrome components, with high blood pressure being the most common. Guidelines for this diagnosis and other children’s non-malignant diseases require additional research.