आईएसएसएन: 2381-8727

सूजन, कैंसर और एकीकृत थेरेपी के अंतर्राष्ट्रीय जर्नल

खुला एक्सेस

हमारा समूह 1000 से अधिक वैज्ञानिक सोसायटी के सहयोग से हर साल संयुक्त राज्य अमेरिका, यूरोप और एशिया में 3000+ वैश्विक सम्मेलन श्रृंखला कार्यक्रम आयोजित करता है और 700+ ओपन एक्सेस जर्नल प्रकाशित करता है जिसमें 50000 से अधिक प्रतिष्ठित व्यक्तित्व, प्रतिष्ठित वैज्ञानिक संपादकीय बोर्ड के सदस्यों के रूप में शामिल होते हैं।

ओपन एक्सेस जर्नल्स को अधिक पाठक और उद्धरण मिल रहे हैं
700 जर्नल और 15,000,000 पाठक प्रत्येक जर्नल को 25,000+ पाठक मिल रहे हैं

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Use of Synthetically Created Secondary Metabolites Generated from Marine Species as Epigenetic Biomarkers and Prospective Cancer Therapy

Maria Conte, Elisabetta Fontana

Seaweed, coral, and sponges are examples of sessile creatures that constantly adapt to the biotic and abiotic elements of the ecosystem. To maintain an ecological niche suited for life, this incredibly intricate and dynamic process frequently leads to various types of competition. As a defensive strategy against the outside environment, a large proportion of marine animals have acquired the ability to produce physiologically active compounds known as secondary metabolites. These organic compounds and their derivatives may have epigenome and disease-related epigenetic machinery modulatory effects. By facilitating the creation of complex chemical compounds with potential therapeutic ramifications, epigenetic alterations also serve as a type of environmental adaptation and give marine animals a competitive edge. By controlling important transcriptional factors associated with cancer's hallmarks through carefully orchestrated molecular mechanisms, bioactive compounds are able to interfere with epigenetic targets. These molecular interactions also create signalling interactions of the tumour microenvironment that are essential to cancer phenotypes. As epigenetic modulators, secondary metabolites originating from marine species and their synthetic derivatives are currently understudied. In this review, we emphasize their benefits and drawbacks as well as possible improvements to cancer therapy.