गैस्ट्रोइंटेस्टाइनल और पाचन तंत्र

अमूर्त

Treatment Results of Anal Cancer: A Single-institution Long-term Experience

Anna Hemer, Annika Holmqvist, Gunnar Adell, Maria Albertsson

Background: Anal and perianal cancer is a rare form of cancer. In this study we report results obtained using external beam radiotherapy with or without concurrent chemotherapy in the treatment of anal cancer. It is a singleinstitute long-term evaluation of 138 patients.

Methods: Retrospective analysis of 138 patients treated with radiotherapy (RT) with or without chemotherapy (CT) for an anal carcinoma (T1-4N0-N3M0).

Results: Overall Survival (OS) was 75% and Disease-free Survival (DFS) 68%. Interruptions in treatment were associated with a lower rate of survival.

Conclusion: This study confirms the outcomes of RT with or without CT in the treatment of anal cancer. High rates of side effects imposed tailored CT and RT as well as improved radiation techniques and better chemotherapy regimens.