गैस्ट्रोइंटेस्टाइनल और पाचन तंत्र

अमूर्त

The Distribution and Histopathological Patterns of Gastrointestinal Tract Endoscopic Biopsies in Al Baha, Saudi Arabia

Thamer Alghamdi, Moataz Mohamed Alhasan Ali, Manal A Khalaf, Omayma Mohamedosman Ibrahim, Mohammed Alshumrani

Endoscopy together with endoscopic biopsy is not solely used for diagnosing the neoplastic and non-neoplastic lesion however additionally to start out an effective treatment, to monitor the course of the disease and its response to therapy and for early detection of complications.

Aim of the study: To determine the histopathological patterns of gastrointestinal tract endoscopic biopsies.

Material and Method: A retrospective histopathology-based study carried out at histopathology laboratory at King Fahad Hospital, Albaha, Saudi Arabia, from Jan 2018 to December 2019. Medical records and histopathology results of all patients referred to the endoscopy unit for gastrointestinal tract endoscopy was retrieved for demographic data and after tissue processing H&E stained slides were examined below microscope for histopathological findings.

Inclusion Criteria: All GIT endoscopic biopsy was taken from each sex and everyone ages and received throughout the specified period was included in the study.

Results: Out of 191 endoscopic biopsies studied 99 were from female patients and 92 were from male patients. An age range of 14 - 97 years was observed .There was a single (0.5%) case from the esophagus, 148 (79%) cases from the stomach. Nine biopsies (4.7%) were derived from the small intestine while biopsies of the colon were within the second rank of biopsies by (16%) comprises 30 cases. 167(87.4%) cases were non-neoplastic, 6 (3.1%) cases were benign neoplasms, three lesions were suspicious for malignancy (1.6%) whereas 15(7.9%) were malignant neoplasms. Histopathology revealed chronic gastritis in 148 cases (77.5%) as the major histopathological finding in all investigated biopsies, of that 100(67.5%) cases were Helicobacter pylori-positive, while colonic adenocarcinoma 12 cases (6.3 %) comprised the most frequently diagnosed malignant lesion.

Conclusion: A wide spectrum of neoplastic and inflammatory lesions was reported in the present study. Chronic gastritis (77.5%) is the major non neoplastic histopathological finding in all investigated biopsies and the majority of that was Helicobacter pylori-positive, while colonic adenocarcinoma (6.3%) comprised the most frequently diagnosed malignant lesion.