फार्माकोलॉजी और टॉक्सिकोलॉजी के विश्व जर्नल

अमूर्त

Potential Exists to Develop Pharmacological Treatments that Target Particular Receptors

Okada Tetsuji

The discovery that no longer all agonists uniformly spark off cell signaling pathways (biased signaling) has noticeably modified the drug discovery procedure for agonists and the method for cure of sickness with agonists. Technological advances have enabled complicated receptor behaviors to be considered independently and via these assays, the bias for an agonist can be quantified. It is expected that therapeutic phenotypes will be linked, thru translational studies, to quantified scales of bias to information medicinal chemists in the drug discovery process.