हमारा समूह 1000 से अधिक वैज्ञानिक सोसायटी के सहयोग से हर साल संयुक्त राज्य अमेरिका, यूरोप और एशिया में 3000+ वैश्विक सम्मेलन श्रृंखला कार्यक्रम आयोजित करता है और 700+ ओपन एक्सेस जर्नल प्रकाशित करता है जिसमें 50000 से अधिक प्रतिष्ठित व्यक्तित्व, प्रतिष्ठित वैज्ञानिक संपादकीय बोर्ड के सदस्यों के रूप में शामिल होते हैं।
ओपन एक्सेस जर्नल्स को अधिक पाठक और उद्धरण मिल रहे हैं
700 जर्नल और 15,000,000 पाठक प्रत्येक जर्नल को 25,000+ पाठक मिल रहे हैं
Karin Eshagh, Chris M Reid, Michael Chan, Grace Y Lin, Thomas Savides and Jason K Sicklick
Groove pancreatitis is a rare form of chronic pancreatitis that has been described by several names including para-duodenal wall cyst, pancreatic hamartoma of the duodenum, cystic dystrophy of heterotopic pancreas, and myoadenomatosis. It is characterized microscopically by the presence of a pseudocyst arising from the “groove” between the duodenum, common bile duct, and pancreatic head. It is thought to be caused by functional and/or anatomical minor papilla obstruction from viscous pancreatic secretions. In turn, this leads to impaired pancreatic enzyme outflow, Brunner’s gland proliferation, and resultant pancreatitis. This often appears as a submucosal mass in the region. Thus, the differential diagnosis ranges from benign pathologies such as Brunner’s gland hyperplasia, leiomyoma, and schwannoma to malignant pathologies such as gastrointestinal stromal tumor and ampullary carcinoma. Herein, we present a case of a middle aged male smoker with a remote history of alcohol abuse that presented with one month of epigastric pain associated with bilious emesis and weight loss. Computed tomography (CT) and endoscopic ultrasound (EUS) revealed a submucosal cystic mass that was obstructing the second portion of the duodenum. Cytology demonstrated crowded groups of atypical epithelioid and spindle cells that were suspicious for a neoplasm. The patient subsequently underwent pancreaticoduodenectomy in order to relieve his duodenal obstruction, as well as to establish a definitive tissue diagnosis. Despite the use of multiple imaging modalities including CT and EUS with fine needle aspirates, the final diagnosis of groove pancreatitis was only made following resection. This case now demonstrate that groove pancreatic often mimics submucosal duodenal tumors and malignant periampullary cancers clinically, radiographically, endoscopically, and cytologically.