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Dysphagia with White Esophageal Exudates: An Eosinophilic Esophagitis Mimic Treated with a Proton-Pump Inhibitor

Anisa Shaker, Karla O’Dell, Shefali Chopra

Eosinophilic Esophagitis (EoE) is a major cause of dysphagia and food impaction. Recognition and diagnosis of EoE have been increasing rapidly, but the role of Proton Pump Inhibitors (PPIs) for the diagnosis of EoE and treatment of esophageal eosinophilia remains controversial. Initial diagnostic algorithms for EoE relied on a PPI trial to distinguish EoE from gastroesophageal reflux disease, a common cause of esophageal eosinophilia.