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Dengue Fever Unmasking the Four Serotypes of the Virus

Hannah Andrews

Dengue fever, often referred to simply as dengue, is a mosquito-borne viral infection that affects millions of people worldwide, particularly in tropical and subtropical regions. This disease is caused by the dengue virus, which is transmitted to humans primarily through the bite of infected female Aedes mosquitoes, primarily the Aedes aegypti mosquito. Dengue fever is a significant global health concern due to its widespread prevalence and potential for severe illness. The virus exists in four distinct serotypes (DENV-1, DENV-2, DENV-3, and DENV-4), and infection with one serotype does not provide immunity against the others. In fact, subsequent infections with different serotypes can increase the risk of severe dengue, also known as dengue hemorrhagic fever or dengue shock syndrome.