संक्रामक रोग और थेरेपी जर्नल

अमूर्त

Burden of Anemia in Malarial Parasite Infection

Jamal M, Hameed A and Imtiaz F

Background: Malaria, being a major health problem in developing world, is a debilitating and at times lethal Infectious disease.
Objective: To observe the frequency and type of anaemia in patients who had malarial infection which may deteriorate the condition.
Design: Cross sectional study
Place and Duration: This study was conducted in two different tertiary care hospitals. From June 2009 to July 2011.
Patients and Method: A total of 834 malaria positive blood samples were taken after taking consent from
patients and their demographic characteristics were noted. Laboratory investigations were done including complete blood count. Complete blood count was performed by automated Coulter counter. The samples with low levels of haemoglobin in the blood were categorized as "anaemic”. All malarial positive cases were reviewed by a haematologist and data was analyzed using SPSS 16.0.
Results: The analysis revealed that, out of total 834 malarial positive samples, 65% females and 35% were males. Age range was 6 months to 50 years in male subjects and 1 year to 70 years in female subjects. 69% come to be Plasmodium vivax and 31% as Plasmodium falciparum. 120 cases (41.5%) in males show low level of haemoglobin (10.5 g%) and 40% among them show the well defined picture of hypochromic microcytic anaemia, while 72 cases (60%) give the picture of normochromic normocytic. In females, 516 cases (94.64%) show the low level of haemoglobin (9.0 g%) and 396 cases show Hypochromic microcytic anaemia, while 120 cases (23.21%) shows the normocytic normochromic blood picture.
Conclusion: In our sample population P.vivax found to be more frequent with hypochromic microcytic anaemia picture associated anaemia (58%), with low haemoglobin levels. Females showed greater prevalence of hypochromic microcytic anaemia as well as low Hb levels as compared to males significantly due to dietary deficiencies and other sources of blood loss.