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An Emerging Model of Word Retrieval in Preclinical Alzheimer's Disease

Vanja Kljajevic

Word retrieval deficit in persons on the Alzheimer’s disease (AD) spectrum has been investigated mostly in AD dementia and, to a smaller degree, in patients with mild cognitive impairment. However, recent evidence suggests that changes in word retrieval abilities are also present in persons at the presumably earliest stage of AD, i.e. in preclinical AD. Considering this evidence as well as previous findings on word retrieval difficulties in cognitively healthy elderly persons, the present paper outlines a novel model of word retrieval in Alzheimer’s disease that is emerging from research in these two fields.